Makhana Enters Nutraceutical League with Rare Compound Discovery in Bihar

In a notable achievement for Indian agriculture, Bihar Agricultural University (BAU), Bhagalpur, has secured a government patent for identifying a rare compound in Euryale ferox, popularly known as makhana or fox nut. This discovery adds scientific value to one of Bihar’s most popular crop.

Natural Compound Found in Makhana

The compound — N-(2-iodophenyl) methanesulfonamide — has the molecular formula C₇H₈INO₂S. It was earlier known only as a synthetic compound, but BAU researchers found it naturally occurring in the perisperm (nutritive tissue) of makhana. This is the first time it has been detected in a natural source.

The research was conducted at BAU’s NABL-certified lab by a team led by Vice-Chancellor Dr. D. R. Singh. Other team members were Director of Research A.K. Singh, and scientists V. Shajeeda Banu, Pritam Ganguly, and Anil Kumar. The patent was officially granted on July 2, 2025.

What are the health benefits of this compound?

This compound is being studied for its anti-microbial and anti-cancer potential. Until now, it was made through complex chemical processes. Finding it in a naturally grown crop like makhana may open new opportunities in the fields of nutraceuticals and wellness-based products.

Dr. Singh said, “This is a proud moment for our team and for the makhana farmers of Bihar. It could add more value to their produce and support better market prices.”

A Boost for Bihar’s Makhana Industry

Bihar is already known for its GI-tagged Mithila makhana, and this discovery could improve its visibility on both national and global platforms. The natural presence of such a compound might attract interest from health startups, agri-businesses, and plant-based food brands.

Growing Opportunities for India

India is the leading producer of makhana, but much of its export potential remains undiscovered. With increasing interest in clean, plant-based superfoods, this discovery may support value-added makhana products — like health snacks, supplements, or even herbal teas.

As global demand for functional foods grows, makhana could soon become more than just a traditional snack.

Read More: Makhana in India: Cultivation, Nutrition & Global Demand

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